News | August 1, 2007

Iongate Automates Active Substance Research On Transporters With SURFE2R Workstation

Frankfurt, Germany - IonGate Biosciences GmbH announces the market launch of SURFE2R Workstation. For the first time a workstation allows a highly automated and efficient drug research on transporters and ion channels.

With this SURFE2R Workstation, IonGate provides the next automated device generation after SURFE2R One and the first to measure 96 sensor array plates. It is especially conceived for applications with higher throughput in pharmaceutical drug screening. Robust and sensitive analytic methods enable the screening of defined compound libraries and the secondary screening of promising substances with high data quality.

The SURFE2R Technology (SURFace Electrogenic Event Reader) permits the direct functional characterization of transporters. This technique also offers a higher data quality than fluorescence-based assays and is substantially simpler and more efficient compared to radioactive methods. Core of the technology is a special biosensor developed by IonGate which measures the activity of transporters through electric charges with a reproducibly high quality.

Transporters, amongst others, play a fundamental role in information processing and the metabolism of any organism. In addition, they also influence the bioavailability of drugs. With the SURFE2R Technology, IonGate offers comprehensive lab automation that is now paving the way to investigate this important new target class fast and economically.

SOURCE: IonGate Biosciences GmbH