Increase Success In Drug Discovery While Reducing Time And Cost With RepliGut®

Altis Biosystems has a patented stem cell platform that recreates the human intestinal epithelium in a high-throughput format for drug screening and microbiome research. Altis has an unrivaled biobank offering multiple tissue donors and regions of the small and large intestine, allowing for long-term use of the same donor and tissue region. Our goal is to reduce the time and cost of drug development with a platform that more accurately reflects native human biology and reduces the need for animal testing.

Altis Biosystems provides a unique in vitro platform that allows for easy characterization of intestinal epithelial cell response to many types of drugs and inflammatory agents. The RepliGut® system provides sequential and distinct proliferative and differentiated phases, which allows for flexibility of screening of both cell types within a single platform. The System can be customized, by utilizing Altis’ unrivaled biobank, to look at different regions of the small intestine and colon from multiple donors to further research faster, easier and more physiologically relevant.