Newsletter | February 4, 2025

02.04.25 -- How Atsena Got Its Gene Therapy To Spread Subretinally To Treat XLRS

FEATURED EDITORIAL

How Atsena Got Its Gene Therapy To Spread Subretinally To Treat XLRS

The company’s novel capsid is delivering therapeutic genes to the fovea without the need for detaching part of the retina.

INDUSTRY INSIGHTS

Dramatic Reduction Of Solvent Usage In Pharmaceutical Spray Drying

Using volatile processing aids to increase drug solubility in more environmentally friendly solvents, like methanol, reduces the amount of solvent required to manufacture amorphous solid dispersions (ASDs).

Achieving Highly Sensitive, Precise Binding Affinity Measurements

Membrane proteins are vital for drug discovery, but traditional characterization techniques can disrupt their structure. This study showcases a new method that maintains native conformation during analysis.

Diagnose Absorption Risks To Improve Preclinical And Clinical Outcomes

Physiologically based pharmacokinetic modeling is a powerful tool for clinical trial design that can be leveraged alongside early development experiments to reduce costs and accelerate timelines.

Effects Of The Ongoing Pandemic On Bupivacaine HCI Supply

Throughout the pandemic, painkiller and sedative demands spiked. Drug manufacturers and CDMOs have become critical in efforts to stabilize the supply of Bupivacaine HCl and other essential drugs.

Hybridoma-Based Antibody Discovery To Support CAR-T Development

Here, we highlight the discovery of diverse and potent human mAbs targeting two tumor antigens, showcasing their potential to enhance CAR-T cell therapies across various cancers.

Achieving Optimal CAR-T Cell Generation

Discover the innovative methods behind CAR-T cell production, from custom plasmid design to lentiviral vector transduction, and explore their potential in revolutionizing cancer treatment.

MOST POPULAR NEWS

Inventia Life Science Launches RASTRUM Allegro

Genialis Advances Biomarker Discovery To Reduce Risk In Cancer Drug Development

BD & Biosero Collaborate To Enable Robotic Integration With Flow Cytometers

AlphaMeld Corporation Expands Collaboration With Kyowa Kirin

Lantern Pharma Unveils Innovative AI-Powered Module

Kenox Pharmaceuticals Expands Capabilities To Strengthen Drug Development Offerings

Saol Therapeutics Announces FDA Acceptance Of NDA For SL1009

Up To $130M To Fuel Drug Discovery And Development At The University Of Chicago

Acellera & Psivant Announce A Strategic Research Collaboration

Corstasis Therapeutics Inc. Announces FDA Acceptance Of NDA For Bumetanide Nasal Spray

Schrödinger Selects Sapio Sciences To Enhance In Silico Drug Discovery From Plasmid To Structure

SOLUTIONS

Analytical Services That Accelerate Drug Development, Commercialization

Organ-Chip Kits For Reproducible Results

Services For Advancing mRNA-LNPs From Bench To Clinic