07.25.23 -- FDA Seeks Input On AI Adoption In Drug Development And Manufacture

Drugs have become more lipophilic and complex in structure over time. Innovative strategies are needed to improve bioavailability of these new drugs.

Spray drying of amorphous dispersions improves solubility and bioavailability that enables supersaturation in the intestine, driving higher rates of absorption when compared to crystalline drug forms.

Ultimately, to serve the highly competitive biopharma and pharmaceutical markets, CDMOs must be adaptable to the culture of the company for whom they are working.

Establishing a relationship with a partner who has the right equipment, scientific expertise, and project management skills is crucial to mitigating risk in tech transfers — and, ultimately, controlling costs.

‘Brick dust’ compounds require additional steps if spray drying is to yield a commercially attractive process. Explore technologies designed to improve drug solubility in organic solvents for spray drying.

Learn from an expert about the process of assay development, qualification, and validation for potency assays and how we can support customers through this vital step.