CYRO Announces Drug Contact Compatibility For Acrylic Compounds

CYRO Industries has announced contact compatibility for a range of pharmaceutical treatment drugs and carriers for its advanced acrylic polymers that are specified for medical device and drug packaging applications. CYROLITE® and XT® polymer acrylic-based multi-polymer compounds and CYREX® acrylic-polycarbonate alloy compounds have passed requirements of the United States Pharmacopoeia (USP) 26, National Formulary 21, 2003 <661> "Physiochemical Tests – Plastics." Compatibility was tested for human insulin solution, Taxol, Heparin, protein solution and common drug treatment carrier solutions.

CYRO's acrylic-based compounds are used for medical applications such as IV adaptors and filter housings, check valves, cassettes, blood handing components, catheter accessories, and rigid packaging trays. CYROLITE and XT polymer compounds are both transparent and impact-modified, ideally suited for applications requiring gamma irradiation, exceptional impact strength and low melt flow rates. CYREX alloys are opaque and offer a high degree of structural integrity, good heat resistance, chemical and gamma resistance, and are ideal for both thin and thick walled applications requiring excellent toughness.

Manufacturers need to assess the potential of leachables in device development and manufacturing, and chemical compatibility is critical when considering primary packaging materials. USP establishes standards to ensure the quality of medicines for human and veterinary use, and it also develops authoritative information about the appropriate use of medicines, as well as standards for strength, quality, purity, packaging, labeling and storage for drugs and excipients.

The suitability of any CYRO compound in given end-use environments is dependent upon various conditions, including, without limitation: chemical compatibility, temperature, part design, sterilization method, residual stresses, and external loads. It is the responsibility of the Manufacturer to evaluate its final product under actual end-use requirements and to adequately advise and warn purchasers and users thereof.

Headquartered in Rockaway, NJ, CYRO Industries is the innovative supplier of specialty acrylic solutions to existing and emerging markets in the Americas. Formed in 1976 as a joint partnership between Cytec Industries and Röhm GmbH & Co., KG, a subsidiary of Degussa AG, CYRO has broad technological and global resources to respond to market demands.