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By Jie Huang, M.D./Ph.D., CSTEAM-Biotech | As stem cells age, their regenerative capacity declines due to accumulated genetic and epigenetic changes. Using CRISPR-Cas, scientists can directly edit these changes or modulate aging-related pathways. |
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| Optimizing Virus Filtration Validation | Article | By Aernout Martens, Cytiva | Explore guidance regarding the effective validation of a virus filtration process in the laboratory, including the fundamentals of viral filtration and an examination of relevant regulatory guidelines. |
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| How Approved Drugs Have Evolved Since The '70s | Article | By Jamie Unwin, Chris Worrall, and Christian Jones, Nanoform | Drugs have become more lipophilic and complex in structure over time. Innovative strategies are needed to improve bioavailability of these new drugs. |
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| "Ultra High” Potency Development And Manufacture | Case Study | Cambrex | A biotech with limited experience in the development and manufacture of high potency compounds sought to develop a process for producing a highly potent API used to treat an unmet oncology need. |
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