Drugs have become more lipophilic and complex in structure over time due to the industry’s move away from natural products. Despite this shift, fully synthetic drugs continue to grow in diversity and complexity. Innovative strategies are needed to improve bioavailability of these new drugs.
Optimizing a drug’s solid form can improve its solubility and bioavailability when further molecular modifications are prohibitive. The Nanoform team reviews solid form strategies for increasing the solubility and oral bioavailability of small molecule drugs.
Innovative technologies are necessary to improve the success rate of new drug candidates and push novel therapies to market. Recent advances in nanoparticle engineering technology promise to accomplish this.
