Newsletter | September 10, 2024

09.10.24 -- Bridge RNAs: Principles, Applications, And Challenges

FEATURED EDITORIAL

Bridge RNAs: Principles, Applications, And Challenges

Bridge RNAs are structured noncoding RNAs that facilitate programmable recombination between target and donor DNA, enabling precise genomic rearrangements. A significant advantage is their modularity.

INDUSTRY INSIGHTS

Formulation Of Crystalline Nanoparticles Enabling Superior Drug Load

Explore how bioavailability of poorly soluble APIs can be improved and patient compliance enhanced by reducing the size or number of tablets that a patient must take to achieve the required dose.

Welcoming The "Era Of ADCs"

Industry expert Dr. Loretta Itri sits down to explore the promise of TRODELVY®️ and other antibody-drug conjugates as transformative treatments for a range of malignancies and intractable diseases.

Optimizing End-To-End Processes To Reduce Costs And Improve Yields

Understand the challenges faced by a large CDMO as well as the solutions that were provided to achieve time savings, cost savings, and the removal of a major downstream process limitation.

Solutions For Accelerated Pharmaceutical Development

Explore an integrated service package designed to simplify and accelerate the development pathway, even for APIs with challenging properties such as low aqueous solubility and poor bioavailability.

Streamlined Selection Of In Vivo Predictive Dissolution Media

Review the design of dissolution media to support biopredictive dissolution testing and a method for selecting practical, physiologically relevant media based on drug, formulation, and GI fluid properties.

Optimized Stability Storage

A healthcare manufacturer facing space constraints and regulatory pressures outsourced their stability storage needs to another company, resulting in reduced costs and focus on core competencies.

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Obsidian Therapeutics Receives FDA RMAT Designation For OBX-115

Arcturus Therapeutics Receives Clearance Of An IND App To U.S. FDA For ARCT-032

Novel Chemical Tool Aims To Streamline Drug-Making Process

BioVie Announces FDA Auth Of IND App For Phase 2 Trial To Evaluate Bezisterim In Long COVID

ERS Genomics And Medicines Discovery Catapult Sign CRISPR/Cas9 License Agreement

QSimulate & JT Announce Strategic Partnership To Accelerate Small Molecule Drug Discovery Technologies

HAYA Therapeutics Collaborates With Lilly To Discover Novel Regulatory Genome Targets For Obesity Using Proprietary RNA Platform

SOLUTIONS

High Potent APIs

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