Application Note

Solutions For Challenging Compounds Using Softgel Innovation

Source: Catalent

Better Development And Formulation Solutions For Challenging Compounds Using Softgel Innovation

For the last 80 years, softgel technology has brought poorly water soluble and/or permeable BCS II & IV compounds to market by improving their bioavailability. Gelatin has predominantly been the ingredient of choice for the softgel shell material for lipid base formulation; its success is demonstrated by the wide range and number of softgel products available on market. The significant interest in semi-solid systems for the potential of extended release profiles has prompted researchers to develop alternative encapsulating systems. Catalent Pharma Solutions has lead research studies to establish that the plant polysaccharides-based OptiShell™ technology can accommodate a wider range of excipients and more molecules.