Components Of An Effective Disinfectant Prequalification Strategy

By Mariana Breña, Analyst II, Christopher Parker, Associate Manager of Microbiology, and Michael Mrvos, Director Sales Testing Services, Cambrex Agawam

Microbial control in pharmaceutical manufacturing facilities is essential to ensure the production of safe, high-quality medicines. Cleaning procedures designed specifically to destroy microbial contaminants that may be present are an important component of any microbial control strategy. The effectiveness of disinfectant regimes employed in these cleaning procedures must be demonstrated to destroy common organisms recovered in the classified areas identified through appropriate microbial identification in trending efforts.

Importance of Microbial Control

To create safe and effective drug products and medical devices, manufacturers spend a significant amount of time and money to research, develop and scale up efficient manufacturing processes. With so much focus on process optimization, it can be easy to lose sight of other equally important tasks, including microbial control.