Newsletter | December 5, 2023

12.05.23 -- Using Automation For Antimicrobial Screening

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FEATURED EDITORIAL

Using Automation For Antimicrobial Screening

A major challenge with antimicrobial drug development is the necessity to test millions of drug compounds in the hope of finding one that will kill a given microbial pathogen. Laboratories are using robotic machines and automated solutions to try growing previously unculturable organisms that might be sources of antimicrobial compounds — and these efforts are finding success.

INDUSTRY INSIGHTS

Embrace A 360-Degree Approach To Biopharmaceutical Testing Services

A 360-degree approach entails full CMC development and analytical release testing in support of biopharmaceutical products in development and in clinical trials — all from one partner.

Early Solid Form Screening To Guide Drug Development

Conducting solid form screening early can help your team select and isolate the ideal lead polymorph to ensure manufacturability and stability while avoiding costs and hiccups down the road.

Design Of Experiments Approach To Enabling Studies For Process Validation

A recent project applied process improvement methodology to the process validation step that ultimately provided not only an optimized, robust process but also an economic advantage.

Particle Engineering For Inhalation Drug Delivery

This article discusses key parameters for choosing the right particle engineering approach to meet dry powder inhaler (DPI) target product profiles for inhalation-based drug products.

Tips For Purifying Cryo-EM Samples

Cryo electron microscopy can help you determine structures for challenging proteins, such as membrane proteins and larger complexes. This presentation offers tips on purifying your cryo-EM samples.

Balancing Cost Efficiencies In The Drug Development Process

Cost efficiencies and expertise again go hand in hand, with companies often outsourcing or partnering primarily to gain access to manufacturing know-how.

Media Selection For In Vitro Testing Of Poorly Soluble Drugs

Lonza principal scientist Deanna Mudie, Ph.D., covers the design of dissolution media to support biopredictive dissolution testing and how the properties of a drug and formulation affect performance.

From Powder To Particles With Jet Milling

Gain valuable insights into the jet milling process and quality by design approach for inhalation drug delivery and their potential applications in drug development.

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