Drug Discovery Online: Digital Marketplace for the drug development industry

Golden Rules For Working With Cell Cultures
Susi and Adi know from their own (sometimes bitter) experience the sort of things that cause problems for them and their colleagues in cell culture bottles in the lab.

Imaging And Analysis Of A High Density Cell Migration Assay
Complex biological or environmental signaling events can lead to cell migration, the movement of cells from one location to another. The migration of cells commonly occurs during both normal biological processes such as the development of an organism or marking pathological events such as cancer metastasis. Automated processes in higher density formats improve throughput greatly increasing the usefulness of performing migration assays at a larger scale. This study evaluated the use of a high density cell exclusion assay in 384- well format for investigation of cell migration using a cell line stably expressing green fluorescent protein (GFP).
Getting The Most Out Of Your Viral Clearance Study
By John Zehmer, PhD, Senior Scientist and Study Director at BioReliance

Conducting a viral clearance study is an important step on the road toward getting your biomolecule into the clinic and on its way to becoming a drug. However, since most companies do not have the systems in place to support a regulated virological study of this kind, this will likely mean engaging a contract research organization (CRO) as a partner. The keys to meeting your goals are solid planning and good communication between your group and your CRO partner. This article provides a high-level review of these processes and will aid in planning for a successful study.
Patheon Surfs Outsourcing Waves And Scoops Up Gallus Along The Way
Jim Mullen, CEO of Patheon parent company DPx Holdings B.V., is at it again.

On the heels of my three-part series with Mullen on the details behind the springtime merger of his company and the pharmaceutical products division of Royal DSM, he has made his next move.

This time it is a strategic entrée into the U.S.-based market for biologics services via an acquisition of privately held Gallus BioPharmaceuticals. With Gallus, Patheon adds new capabilities at well-established sites with name-brand clientele, in St. Louis, Mo. and Princeton, N.J., to its global locations in Groningen, the Netherlands and Brisbane, Australia.
Systematic Method Development Of UPC2 Conditions Using Opioid Drugs
This application note uses a panel of natural and synthetic opioid drugs to demonstrate the use of a systematic screening strategy for UPC2 method development. By Jonathan P. Danaceau, Kenneth J. Fountain, and Erin E. Chambers, Waters Corporation

Blood Bank Products Catalog

The blood bank products catalog features blood bank refrigerators, freezers, and accessories that offer a wide selection, cooling capacity, accurate temperature control, alarm monitoring, inventory management, and reliability for critical storage requirements...

Reliance® 9800 Pharmaceutical Grade Washer

The Reliance 9800 Pharmaceutical Grade Washer is intended for thorough cleaning of various materials and components used in the cosmetic and pharmaceutical manufacturing process industries, such as large vessels, containers, drums, Integrated Bulk Containers (IBC's), pallets, blenders hoppers, and other large items.