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Featured Products
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Diode-Array Spectrometers
The AH4100 Spectrometer is a miniature single-beam spectrometer offering excellent performance in a rugged and compact package.
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Downward Transfer System
The SuPerCharge TurboBlotter system is a downward transfer system designed for rapid nucleic acid blotting...
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Medical Devices And Equipment
Marken has trained professionals with global expertise to protect and manage the logistics of Medical Devices, Diagnostic Equipment, and Medical Components including sensitive microchips and Surgical equipment with expertise in ECG/ABM devices, Stents, Pace makers, and investigator site specimen separation devices.
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Culex Automated In Vivo Sampling System
Rely on BASi for practical solutions to in vivo sampling with minimal human intervention. Perform automated blood sampling, automated dosing, microdialysis collection, and more in awake and freely moving animals.
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Drug Safety Evaluation
MPI Research offers comprehensive services to help determine the safety of life-changing compounds and assist in bringing them to the marketplace as rapidly as possible.
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Golden Hour® Technology
Originally created in response to the need for an effective combat-environment thermal container on the battlefields of Afghanistan, patented Golden Hour Technology utilizes a unique Thermal Isolation Chamber (TIC®) System and superior PCM custom-formulated with a freeze/thaw threshold selected specifically for the necessary temperature range.
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ADMET-PK and Bioanalytical Services
The ADMET-PK Team at SCYNEXIS understands the challenges in optimizing the bioavailability of a molecule and is well-equipped to determine compound adsorption, distribution and metabolism with state-of-the-art instrumentation and techniques. They are fully-integrated in our efforts to provide fast and efficient medicinal chemistry decision support for rapid hit seeking, H2L, lead optimization and candidate selection. Lead optimization projects are guided by a portfolio of in vitro DMPK assays including plasma stability studies, cytochrome P450 inhibition assays and metabolite identification leading to in vivo animal studies to determine PK parameters. We offer fully-integrated contract research, discovery and development services including Drug Discovery, ADMET-PK, Bioanalysis and Process Chemistry & GMP API manufacturing.
Success with SCYNEXIS
Our team works in state-of-the-art facilities with access to a comprehensive suite of high-end biological assays and bioanalytical instrumentation. We have successfully developed and delivered numerous assays to our clients’ drug discovery and development programs including:- CNS/brain tissue exposure for Stage II Human African Trypanosomiasis (HAT)
- Ocular tissue distribution of novel drug candidates for dry eye indications
- Prodrug and parent monitoring to improve bioavailability and release profiles
In Vitro ADMET Capabilities
- Rodent & Large Animal PK
- Allometry
- Routes of Elimination
- Tissue/CNS Distribution
- PK-PD
- Metabolite Profiling
Bioanalytical Capabilities
- Method Development
- Sample Preparation
- Tissue Extractions
- Microtiter and Online SPE
- Metabolite ID
- Liquid Handlers
- PK Screening
- Tandem-MS (MRM and SRM)
- Triple-Quadrupole MS
- HTS Platforms (Beckman, Tecan, LEAP)
- Prodrug Studies
- PD Studies
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Quick To Market™
A unique Patheon-only program that offers accelerated transfer of commercially available products from an existing manufacturing plant to a plant within Patheon’s network.
Featured Suppliers
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SCYNEXIS, Inc.
SCYNEXIS, Inc. is a premier drug discovery and development company delivering effective and innovative drug pipeline solutions to human and animal health pharmaceutical and global health partners.
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Marken
Founded in 1980, Marken is focused on supporting Life Science companies assure the quality and integrity of clinical trial specimens and vital medications through the logistics chain. For nearly two decades, Marken has extended the reach of Pharmaceutical companies, research laboratories and clinical trial research organizations bridge the distance between patients and life science investigative resources.
Industry Events
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Medical Devices � EU Directives Guidance CE Marking and ISO Standard Certifications
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Active Pharmaceutical Ingredient (API) and Drug Product Specifications
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Aseptic Processing in the Manufacture of Biotech and Pharmaceutical Products
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