Newsletter | September 8, 2022

09.08.22 -- Why Make The Switch To Multi-Column Chromatography?

 
5 Reasons To Switch To Multi-Column Chromatography
 

Multi-column chromatography (MCC) solutions offer several advantages, and we’ve put together the top five most compelling ones in this infographic. See for yourself how MCC technologies can transform your existing batch processes and provide a first step in your exploration of continuous processing.

Multi-Column Chromatography Process Modeling For Process Performance Prediction
 

Continuous multi-column chromatography has the potential to reduce resin and buffer usage and costs of a bind and elute process by increasing process productivity and throughput. This poster shows one approach to generate a predictive performance model for a mAb process and defines the difference that more process columns provide when intensifying feed concentration.

Protein A Resin Reduction Achieved With Process Transfer From Batch To BioSMB
 

A biopharmaceutical manufacturer was looking to reduce the operating costs of existing purification steps with high resin costs. Learn how transferring an existing batch chromatography process into a multi-column format and then scaling up that process to a continuous perfusion run resulted in a dramatic reduction in protein A resin requirements.

Increased Productivity At The mAb Capture Step
 

Read how an easy conversion from a single column to a multicolumn format enabled this biopharma company to reduce protein A consumption by 80%. This allowed for reductions in overall cost and up-front investment in consumables with no change to the quality of the resulting product.