Newsletter | February 11, 2020

02.11.20 -- Why Are Lipid Formulations Commonly Used To Enhance Bioavailability?

Industry Insights
Process Effects On Drug Product Quality In Pharmaceutical Manufacturing — A Validated Measurement Process
White Paper | GE Healthcare Life Sciences

This white paper discusses the importance of understanding how critical process parameters can impact a product’s critical quality attributes, and how a systematic approach with validated SPR assays can help in this respect.

Developability Assessment Of Small Molecules
White Paper | GVK Biosciences

Developability assessment or preformulation studies of small molecule is an important part the of drug discovery process leading to selection of New Chemical Entities (NCEs) for clinical studies. This white paper dives deeper into why we need developability assessment as well as its processes.

Guidelines For Phasing Variants Using Bio-Rad Droplet Digital System
Application Note | Bio-Rad Laboratories, Inc.

We describe a Droplet Digital PCR-based method, Drop-Phase, which allows users to quickly and accurately phase genomic variants. We successfully phased pairs of CFTR variants and show the methodology can measure linked species that are up to 210 kb apart. This method can be used to phase variants discovered through sequencing or to screen unsequenced individuals for a particular haplotype of interest for clinical trials.

Why Are Lipid Formulations Commonly Used To Enhance Bioavailability?
Webinar | Thermo Fisher Scientific

Thermo Fisher Scientific's Kaspar van den Dries and Helena Teles discuss potential mechanisms of increased absorption with lipid formulations and appropriate screening tools that are used during the development approach of these formulations, as well as scale up and industrialization considerations. 

Antibody Purification And Immunoprecipitation
GE Healthcare Life Sciences
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