Newsletter | July 14, 2020

07.14.20 -- Using Drug Screens And CRISPR To Make Better Cancer Drugs

 
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Accelerate Complex Molecule Development By Optimizing Chemical Synthesis And Formulation

The importance of optimizing the chemical synthesis and formulation processes in complex molecule development.

Codetection Of Viral Pathogen RNA And DNA Using One-Step Multiplex RT-qPCR

RT-qPCR is a well-established method for the detection, quantification, and typing of different microbial agents in the areas of clinical and veterinary diagnostics, as well as food safety. There are multiple benefits of this technology. In this application note, we demonstrate a sensitive codetection of viral RNA and DNA targets in a multiplex setting using a novel one-step multiplex RT-qPCR supermix.

How To Pick The Right CDMO For Late-Phase Clinical Trials

For pharmaceutical companies without their own facilities, choosing the right partner for late-phase clinical trials and commercial production is a critical consideration in developing parenteral products. This article examines some of the key criteria for selecting the right CDMO partner and includes a case study that shares some challenges involved in a late-phase technology transfer for a parenteral product.

Purifying Tagged Proteins Using ÄKTA Go Protein Purification System

ÄKTA go is a small and compact liquid chromatography system that allows researchers to perform routine protein purification with ease while allowing for efficient use of bench and cold cabinet space.

Tufts Study: Advantages Of Single-Source Drug Development, Manufacturing

A recent study by the Tufts Center for the Study of Drug Development (CSDD) compared cycle times and development economics between multi- and single-source CDMO models.

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