Brochure: Preclinical Toxicology Services

Our AAALAC-accredited laboratory has been providing clients with drug safety and toxicology data for over 30 years. Located on a 52-acre campus in a rural setting near Evansville, Indiana, our preclinical research facility occupies a total of 90,000 square feet in 11 buildings. BASi is large enough to have all the resources and experience to complete your projects expertly and on time, yet small enough to be flexible and responsive.

BASi provides clients with fast, reliable, preclinical in-life and pathological data in compliance with federal guidelines. Clinical pathology, clinical chemistries, analytical method development and validation, PK/TK data analysis and histopathology laboratories offer in-house assessment of biological samples and test articles.

Toxicology Services include:

• General toxicology services
  • Acute
  • Sub-chronic
  • Chronic
• Carcinogenicity studies
• Behavioral toxicology
• Immunotoxicology and biomarkers
• Clinical chemistry and pathology panels
• Necropsy and histology with special stains
• Pharmacokinetics and drug metabolism

Pre-IND Studies Required for Phase I Trials

• Acute Toxicity
• Subchronic Toxicity
• Genetic Toxicity
• Safety Pharmacology
• Toxicokinetics

Post-IND Studies Required for an NDA

• Chronic Toxicity
• Carcinogenicity
• Reproductive Toxicity