Application Note

Process Economic Simulation For Scalable Production Of Adenovirus

Source: GE Healthcare Life Sciences
Process Economic Simulation For Scalable Production Of Adenovirus

This application note discloses process economic modelling of a modern start-to-finish adenovirus production process. The novel process was compared with a reference process in both stainless steel and single-use configurations across various production scales and scenarios. The process based on modern tools and technologies was generally shown to be the most cost-efficient option of the investigated alternatives. Process configurations using single-use equipment wherever possible were also shown to be more cost-effective than corresponding configurations using primarily stainless-steel equipment.