Industry Insights
Cut It Out: The Role Of Gene Editing Technologies In Combating HIV
Article | By Bruce K. Brown, Ph.D., Thermo Fisher Scientific

Despite the public attention and large population impacted by HIV, developing a cure has been particularly difficult. To successfully cure an infected individual the virus would need to be fully eradicated from their body, which is difficult because HIV is extraordinarily good at hiding in a person’s cells. Anti-retroviral therapy (ART) drugs have been very effective at keeping viral infection below detection limits, but the drugs cannot reach these hiding places, or “latent reservoirs.”

Quality By Design In Biopharma R&D: Bringing Quality Forward Pays Off
Article | By Tim Moran, Dassault Systemes Americas

Once primarily considered a focus in downstream drug development and manufacturing, quality now demands just as much attention in upstream discovery research.

Imaging Principles And Methods
E-Book | GE Healthcare Life Sciences

A theoretical overview and practical guide to protein imaging and quantitation.

A Novel Cell-Based Screening Assay For Cholesterol Biosynthetic Pathway Inhibition Using The RapidFire HTMS Platform
White Paper | GVK Biosciences

A client was exploring the possibility of re-purposing an internal collection of antifungal CYP51A1 inhibitors for targeting cancers. GVK BIO was commissioned to enable the such project. Learn how a CYP51A1 inhibitor screening assay using the RapidFire HTMS method was deemed to be optimized, and screening of client compounds was enabled with an acceptable throughput and in a cost-effective manner.

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