Newsletter | August 23, 2022

08.23.22 -- Increasing The Efficiency Of Drug Development With Preclinical Testing Using Human Intestinal Stem Cells

 
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Increasing The Efficiency Of Drug Development With Preclinical Testing Using Human Intestinal Stem Cells

More efficient development of drugs with attractive side effect profiles requires robust, easy-to-use, cost-effective in vitro gut models that are physiologically representative of the human intestinal tract.

Simultaneous Spray Drying For Combination Dry Powder Inhaler Formulations

Three combination case studies are demonstrated, in which bevacizumab is paired with erlotinib, cisplatin, or paclitaxel in a dry powder inhaler formulation.

Balancing Cost Efficiencies In The Drug Development Process

Cost efficiencies and expertise again go hand in hand, with companies often outsourcing or partnering primarily to gain access to manufacturing know-how.

Quantitating Binding Similarities In IgG Fcγ Receptor Analysis

Critical quality attributes are fundamental to regulatory compliance in drug development and manufacturing. Learn how surface plasmon resonance has been applied for protein characterization of antibody effector function.

Inclusion Bodies: Mother Nature's Help Or Hindrance?

The pros and cons of soluble and insoluble processes: isolating, solubilizing, and properly refolding, and strategies to improve the performance of IB processes.

Short-Term Solution Or Long-Term Strategy? Planning For Outsourced Drug Development Shifts

As we look forward to the future of drug development, a panel comprising industry consultants and early development experts discussed examining new short- and long-term CDMO and supply chain strategies.

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