How To Design An HPAPI Plant And Prove The Effectiveness Of Its Containment Systems

Dr. Friederike Hermann, Head of Occupational Hygiene and Biosafety at the Lonza site in Visp, Switzerland provides her deep expertise on how to design an HPAPI plant and prove the effectiveness of its containment systems.

• Bringing together the requirements of the production team, research chemists and occupational health
• Evaluating the right containment that meets the needs of all the process steps and stakeholders
• Testing its effectiveness, first using a surrogate already during the mock up study and then with the HPAPI itself during production

Dr. Friederike Hermann is a member of the Health Commission for the site, where more than 3,000 people are employed, and is a certified hygienist through the Swiss Society of Occupational Hygiene. Friederike joined Lonza in 2001 as an Analytical Chemist in the Environmental Department before transitioning to the field of Occupational Hygiene. She contributed significantly in the setup of production facilities at Visp for highly potent active pharmaceutical ingredients (HPAPIs). She is a member of the steering committee for the Community of Practice (CoP) on Containment for the International Society for Pharmaceutical Engineering (ISPE) DACH affiliate and is a member of the MAK Commission for Switzerland.