Newsletter | November 11, 2021

11.11.21 -- Dissolution Media Design To Support Biopredictive Dissolution Testing

 
How Does Media Selection Impact Performance Testing Of Poorly Soluble Drugs?
 

The efficient development of robust oral drug products requires the use of biopredictive in vitro dissolution methods that can evaluate how the interplay between drug formulation and GI fluid properties impacts bioperformance.

Efficient Development Of Oral Drug Products: Selecting A Dissolution Media
 

With so many different media available that vary widely in properties and composition, it is important to know how to select a dissolution media that can effectively test formulation robustness.

Q&A: A Range Of Dissolution Media Properties And How They Compare
 

Deanna Mudie Ph.D., principal scientist, answers questions about the design of dissolution media and how the properties of a drug and formulation affect dissolution performance in these media.

Streamlined Selection Of In Vivo Predictive Dissolution Media
 

Explore the design of dissolution media to support biopredictive dissolution testing and a method for selecting practical, physiologically relevant media based upon drug, formulation, and GI fluid properties.

Selecting In Vitro Dissolution Methodologies For Amorphous Solid Dispersions
 

With the availability of so many types of in vitro dissolution tests, how do you determine which one will be most effective in predicting in vivo performance of your BCS II or IV drug product?