Application Note

Adenovirus Production In Single-Use Xcellerex™ XDR-10 Bioreactor System

Source: GE Healthcare Life Sciences
Adenovirus Production In Single-Use Xcellerex™ XDR-10 Bioreactor System

This application note describes the production of adenovirus in HEK293 cells cultured in HyClone™ CDM4HEK293 culture medium. Early process development was performed in shake flask cultures, aiming for a suitable process for scaleup to single-use bioreactor culture. The results indicate a robust and scalable adenovirus production process.

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