10.04.22 -- 3 Tips For Purifying His-Tagged Proteins

Tags simplify purification and enable scientists to use standard protocols while also improving the yield, purity, and solubility of the protein of interest.

Throughout the pandemic, painkiller and sedative demands have spiked. Drug manufacturers and CDMOs have become critical in efforts to stabilize the supply of bupivacaine HCl and other essential drugs.

In this scientific brief we evaluate the performance of the Pall Nucleic acid binding (NAB) Nanosep centrifugal device for nucleic acid isolation.

With a complete picture of the parameters that control each step during manufacturing, chemists can monitor and control individual reactions to optimize the overall production process.

It is important to consider several factors in the overall development approach during the early phases in order to de-risk late-phase development.

Topical products, whether prescription dermatological drugs or over-the-counter lotions, creams, or gels, present unique challenges in terms of development and manufacturing.

Following several mergers and acquisitions, a biopharmaceutical company had to manage an increasing amount of data from disparate online and offline sources. A solution allowed them to access data from various sources and to feed other systems with data quickly to support the company’s digital science and manufacturing informatics strategies.

Comprehensive diligence around a target before starting a discovery program can make the difference between success and failure.

Manufacturing complex and highly potent ADC treatments presents unique challenges. Get an insider look at how these treatments make it from development to commercialization.