FEATURED EDITORIAL
Achieving bioequivalence for complex generics is an intricate task. This article describes an approach using in vitro–in vivo correlation, PBMK modeling, and more.
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- 2024 LIMS Trends
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- 8 Key Takeaways Of The Proposed FDA Modernization Act 3.0
FEATURED APPLICATION CONTENT
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Discover a first-of-its-kind human LF-Chip containing B, T, plasma and antigen-presenting cells to test functional immunization responses to vaccines and adjuvants in vitro.
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A Bone Marrow-Chip (BM-Chip) was created to recapitulate relevant hematopoietic cell types in a three-dimensional (3D), mechanically active next-generation in vitro model.
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Learn how Organ-Chips are being used to rapidly identify promising treatments, investigate virus evolution, and analyze how mechanical forces influence the innate immune response to viral infections.
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This study examines the expansion, functionality, and phenotype of CAR-T cells cultured in the CellGenix® GMP T cell culture medium (TCM) compared to other commercially available T cell media.
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This study demonstrates the automated magnetic isolation of CD4/CD8+ cells from fresh or frozen leukapheresis using a functionally closed cell processing system paired with a modular application.
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Explore key process operations, some of the challenges in manufacturing high-concentration biologics, and factors to consider for process optimization.
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Discover how an Organ-Chip can be used to create a comprehensive recapitulation of the proximal tubule, addressing the need for more human-relevant preclinical models in the pharmaceutical industry.
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Discover an Intestine-Chip that integrates the robust cell sourcing of organoids with Organs-on-Chips technology to overcome experimental limitations and yield a closer-to-human transcriptomic profile.
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There is a growing need for more human-relevant preclinical models. Explore how Organ-Chips offer a viable solution and can be used to create a comprehensive recapitulation of the liver sinusoid.
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Learn about the development and characterization of Organ-Chips and what makes them the most comprehensive model of the colonic epithelial-endothelial interface that is commercially available.
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Organ-on-a-Chip technology has emerged as a solution to the limitations of conventional preclinical models. Learn how Liver-Chips can be used to test the delivery efficiency and safety of AAV vectors.
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Traditional models for studying inflammatory bowel disease (IBD) often fall short. See how the Colon Intestine-Chip was used to model the progression of IBD driven by immune cells more completely.
FEATURED NEWS HEADLINES
- A New Generation Of Antidepressant Drug Precision Treatment Based On Revolutionary AI Technology Is Born
- CureVac And MD Anderson Enter Strategic Collaboration To Develop Novel Cancer Vaccines
- Improving Drug Development With A Vast Map Of The Immune System
- Scripps Research Chemists Devise Easier New Method For Making A Common Type Of Building Block For Drugs
- Scientists Find New Ways To Convert Inhibitors Into Degraders, Paving The Way For Future Drug Discoveries
- Global Collaboration To Combat Chronic Lung Infection
- Tr1X Announces FDA Clearance Of First Investigational New Drug Application For TRX103, An Allogeneic Regulatory T-Cell Therapy To Treat Autoimmune Diseases
- BioCity Announces FDA Clearance Of The Investigational New Drug Application For Its First-In-Class Antibody Drug Conjugate Targeting Glypican 3
- Sartorius And TheWell Bioscience Partner To Enable More Accurate Predictions In Drug Discovery
- Invenra Inc. Announces A Strategic Research Agreement With Astellas Pharma In Therapeutic Bispecific Antibody Discovery
ARCHIVED NEWSLETTER
- 04.16.24 -- 8 Key Takeaways Of The Proposed FDA Modernization Act 3.0
- 04.15.24 -- Successfully Navigate The Path To IND Submission
- 04.11.24 -- The Business of Biotech: Leaders in ADC Technologies
- 04.09.24 -- PROTACs And Molecular Glues: Rethinking What Is Possible
- 04.04.24 -- See how Organ-Chips are Transforming Drug Development for Cancer, Toxicology, Cell & Gene Therapy, and More!