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NOVOstar Microplate Reader for Cell-based Assays
BMG LABTECH, GmbH
•Brochure: NOVOstar Microplate Reader For Cell-based Assays
The NOVOstar is an exciting product for cell-based kinetic assays and research development. Previously, cell-based assays required the use of expensive HTS equipment, which lead to limited accessibility for scientists in the assay development stage. The NOVOstar offers the right equipment necessary for cell-based assays as well as any other assay suitable for the microplate format.
Detection modes
- Fluorescence Polarization
- Fluorescence Intensity - including FRET
- Time-Resolved Fluorescence - including DELFIA®
- High-Performance Luminescence (flash and glow) - DLReady™ certified
- Absorbance - UV/Vis with path length correction
Wide range of applications
Due to its integrated programmable pipettor system, the NOVOstar is especially well-suited to screen large numbers of compounds in kinetic cell-based assays or to create a dose response curve by measuring a wide range of analyte concentrations. Applications that the NOVOstar is targeted for include:
- Ca2+ measurements (e.g. Ca2+flux with Fura-2, Indo-1, FLUO-3/4)
- Membrane potential studies
- Intracellular pH
- Measurement of intracellular ionic changes
- Fluorescent reporter gene assays
- Traditional fluorescence assays involving up to eight excitation and emission pairs.
Exceptional technologies
The NOVOstar has a dual microplate carrier that allows the user to designate a reagent and measurement microplate. Furthermore, a transfer pipet is incorporated into the design for plate-to-plate transfers along with access to three reagent stations providing you with flexibility in assay design. In addition, the unit has up to two injectors that offer the same variable delivery volume and injection speed as other BMG LABTECH OPTIMA instruments. Incubation, shaking, user-defined kinetic sampling rates, and bottom reading are all features of the NOVOstar. The NOVOstar also incorporates heating plates above and below the entire plate movement area for uniform incubation up to 45°C or even 60°C.
NOVOstar software package
The NOVOstar comes with BMG LABTECH's established Reader Control software and comprehensive Data Analysis Software, MARS. The highly intuitive software provides limitless possibilities for test set up where it is needed, but also offers a "Quick-Start" mode for running routine analysis with just 3 mouse clicks. In MARS, a Wizard guides the user through the entire data analysing process. Additionally, a Template Manager can be used for building complex data processing protocols. Improved robotic integration capabilities, digital signature and FDA 21 CFR part 11 compliance of MARS complete this software package.
•Brochure: NOVOstar Microplate Reader For Cell-based Assays
