Datasheet: Q And S HyperCel™ Chromatography Sorbents

High productivity ion exchangers for protein capture and separations

• High dynamic binding capacity at short (2 minutes) residence time
• Excellent flow rate properties
• Different selectivity and salt sensitivity for capture or intermediate purification steps

Product Description
Q and S HyperCel sorbents are composed of a rigid cellulose matrix that has excellent flow properties and generates low backpressure, compatible with the needs of large-scale protein production. Q and S HyperCel sorbents are available in a variety of packagings as well as convenient prepacked PRC columns designed for fast method optimization and selectivity screening. Q and S HyperCel sorbents are supplied in 1 M NaCl containing 20% ethanol as a slurry or as a moist cake. Custom packaging to meet specific manufacturing requirements is available on request.

Q and S HyperCel sorbents have a chemical stability that ensures simple clean-in-place (CIP) and storage. For standard CIP, 0.5 – 1 M NaOH treatment is recommended, while long-term storage in 10 – 100 mM NaOH is possible.

Features and Benefits

• High dynamic binding capacity for enhanced process productivity: smaller columns, lower buffer requirements, faster operations.
• Excellent flow properties and easy packing/unpacking.
• Small re-equilibration volumes for buffer savings.
• Protein selectivity and salt sensitivity.

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