DRUG DISCOVERY FEATURED ARTICLES & APPLICATIONS

  • Tools for the Design of Vaccines to Help Reduce Clinical Failure
    Tools for the Design of Vaccines to Help Reduce Clinical Failure

    If you are involved in the pharma industry, then you are interested in saving lives. In the area of preventative medicine, therapeutic vaccines have proven to have a tremendous impact on the ability to save millions of lives. Similar to pharmaceuticals, vaccine development can take over 10 years and less than 10 percent of candidates reach commercialization. Reducing the cost of failure and increasing the chances of clinical success for vaccines is beneficial to both the pharma industry and those being treated for or protected from disease.

  • Patheon Surfs Outsourcing Waves And Scoops Up Gallus Along The Way

    Jim Mullen, CEO of Patheon parent company DPx Holdings B.V., is at it again.

    On the heels of my three-part series with Mullen on the details behind the springtime merger of his company and the pharmaceutical products division of Royal DSM, he has made his next move.

    This time it is a strategic entrée into the U.S.-based market for biologics services via an acquisition of privately held Gallus BioPharmaceuticals. With Gallus, Patheon adds new capabilities at well-established sites with name-brand clientele, in St. Louis, Mo. and Princeton, N.J., to its global locations in Groningen, the Netherlands and Brisbane, Australia.

  • Systematic Method Development Of UPC2 Conditions Using Opioid Drugs

    This application note uses a panel of natural and synthetic opioid drugs to demonstrate the use of a systematic screening strategy for UPC2 method development. By Jonathan P. Danaceau, Kenneth J. Fountain, and Erin E. Chambers, Waters Corporation

  • A Single-Injection UPC2 Method For Fast And Simultaneous Separation Of Nine Fat-Soluble Vitamins

    Fat-soluble vitamins(FSVs) include vitamins A, D, E, K and carotenoids such as β-carotene. The FSVs are involved in complex metabolic reactions related to important biological functions such as vision (vitamin A), calcium absorption (vitamin D), antioxidant protection of cell membrane (vitamin E), and blood coagulation (vitamin K). By Rui Chen, Jinchuan Yang, and John McCauley, Waters Corporation

  • Lipid Class Separation Using UPC2/MS

    A flexible, universal method was developed for the analysis of inter-class separations of neutral and amphipathetic lipids. By Michael D. Jones, Giorgis Isaac, Giuseppe Astarita, Andrew Aubin, John Shockcor, Vladimir Shulaev, Cristina Legido-Quigley, and Norman Smith

More From Featured Articles

LATEST NEWS

  • Researchers Develop Faster Cancer Drug Discovery Platform
    Researchers Develop Faster Cancer Drug Discovery Platform

    University of Michigan researchers have developed a new method for identifying potential cancer therapeutics that speeds up the traditionally slow drug discovery process. Using this new platform, the researchers were able to identify a novel antibody which is currently being evaluated as a potential treatment for breast, ovarian, and other cancers.

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Process Validation: Ensuring Compliance With Multiple Standards

November 4, 2014
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November 5 - 7, 2014
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November 6 - 7, 2014
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