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DRUG DISCOVERY FEATURED ARTICLES & APPLICATIONS

  • Imaging And Analysis Of A High Density Cell Migration Assay

    Complex biological or environmental signaling events can lead to cell migration, the movement of cells from one location to another. The migration of cells commonly occurs during both normal biological processes such as the development of an organism or marking pathological events such as cancer metastasis. Automated processes in higher density formats improve throughput greatly increasing the usefulness of performing migration assays at a larger scale. This study evaluated the use of a high density cell exclusion assay in 384- well format for investigation of cell migration using a cell line stably expressing green fluorescent protein (GFP).

  • Getting The Most Out Of Your Viral Clearance Study

    By John Zehmer, PhD, Senior Scientist and Study Director at BioReliance

    Conducting a viral clearance study is an important step on the road toward getting your biomolecule into the clinic and on its way to becoming a drug. However, since most companies do not have the systems in place to support a regulated virological study of this kind, this will likely mean engaging a contract research organization (CRO) as a partner. The keys to meeting your goals are solid planning and good communication between your group and your CRO partner. This article provides a high-level review of these processes and will aid in planning for a successful study.

  • Patheon Surfs Outsourcing Waves And Scoops Up Gallus Along The Way

    Jim Mullen, CEO of Patheon parent company DPx Holdings B.V., is at it again.

    On the heels of my three-part series with Mullen on the details behind the springtime merger of his company and the pharmaceutical products division of Royal DSM, he has made his next move.

    This time it is a strategic entrée into the U.S.-based market for biologics services via an acquisition of privately held Gallus BioPharmaceuticals. With Gallus, Patheon adds new capabilities at well-established sites with name-brand clientele, in St. Louis, Mo. and Princeton, N.J., to its global locations in Groningen, the Netherlands and Brisbane, Australia.

  • Systematic Method Development Of UPC2 Conditions Using Opioid Drugs

    This application note uses a panel of natural and synthetic opioid drugs to demonstrate the use of a systematic screening strategy for UPC2 method development. By Jonathan P. Danaceau, Kenneth J. Fountain, and Erin E. Chambers, Waters Corporation

More From Featured Articles

LATEST NEWS

  • Pfizer Receives U.S. FDA Accelerated Approval Of IBRANCE (palbociclib)

    Pfizer Inc. recently announced the U.S. Food and Drug Administration (FDA) has granted accelerated approval of IBRANCE (palbociclib), in combination with letrozole, for the treatment of postmenopausal women with estrogen receptor-positive, human epidermal growth factor receptor 2-negative (ER+/HER2-) advanced breast cancer as initial endocrine-based therapy for their metastatic disease

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FEATURED PRODUCTS AND SERVICES

Blood Bank Products Catalog

Blood Bank Products Catalog

The blood bank products catalog features blood bank refrigerators, freezers, and accessories that offer a wide selection, cooling capacity, accurate temperature control, alarm monitoring, inventory management, and reliability for critical storage requirements...
The FLIPR<sup>384</sup>  System - Fluorometric Imaging Plate Reader

The FLIPR384 System - Fluorometric Imaging Plate Reader

In today’s screening laboratories, the demands for increasing throughput, sample volume conservation, and lower costs are paramount
PharmacoEconomics & Outcomes News

PharmacoEconomics & Outcomes News

PharmacoEconomics & Outcomes News brings you up-to-date summaries of important pharmacoeconomic and outcomes A
Clinical Trial Material Manufacturing

Clinical Trial Material Manufacturing

Patheon offers expertise in GMP manufacturing of clinical trial materials to support Phase I appropriate dosage forms with fit for purpose formulations. 

Workbench

Workbench

The Assay TekBench is a part of a family of workbenches designed to perform microplate assays, replication, reformatting, sealing/unsealing and long-term storage under a low temperature, inert gas atmosphere
Reliance&reg; 9800 Pharmaceutical Grade Washer

Reliance® 9800 Pharmaceutical Grade Washer

The Reliance 9800 Pharmaceutical Grade Washer is intended for thorough cleaning of various materials and components used in the cosmetic and pharmaceutical manufacturing process industries, such as large vessels, containers, drums, Integrated Bulk Containers (IBC's), pallets, blenders hoppers, and other large items.
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INDUSTRY EVENTS

Biotherapeutics Analytical Summitt

March 9 - 13, 2015
Baltimore, MD

It's Ten O'Clock. Do You Know Where Your Trial Master File Is?

March 10, 2015
1pm-2:30pm EDT, Online Training

The Top Method Validation Mistakes – And How to Avoid Them

March 11, 2015
1pm-2:30pm EDT, Online Training
More Events....

 UPCOMING TRAINING COURSES

It's Ten O'Clock. Do You Know Where Your Trial Master File Is?

March 10, 2015
1pm-2:30pm EDT, Online Training

The Top Method Validation Mistakes – And How to Avoid Them

March 11, 2015
1pm-2:30pm EDT, Online Training

Preparing eCTD Submissions: A Step-By-Step Guide

March 17, 2015
1pm-2:30pm EDT, Online Training
More Upcoming Courses

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