• A Single-Injection UPC2 Method For Fast And Simultaneous Separation Of Nine Fat-Soluble Vitamins

    Fat-soluble vitamins(FSVs) include vitamins A, D, E, K and carotenoids such as β-carotene. The FSVs are involved in complex metabolic reactions related to important biological functions such as vision (vitamin A), calcium absorption (vitamin D), antioxidant protection of cell membrane (vitamin E), and blood coagulation (vitamin K). By Rui Chen, Jinchuan Yang, and John McCauley, Waters Corporation

  • Lipid Class Separation Using UPC2/MS

    A flexible, universal method was developed for the analysis of inter-class separations of neutral and amphipathetic lipids. By Michael D. Jones, Giorgis Isaac, Giuseppe Astarita, Andrew Aubin, John Shockcor, Vladimir Shulaev, Cristina Legido-Quigley, and Norman Smith

  • Fast Separation Of Triacylglycerols In Oils Using UltraPerformance Convergence Chromatography (UPC2)

    Studies using UPC2 coupled with ultraviolet (UV) detection, mass spectrometry (MS), and evaporative light scattering (ELS) detection for the separation of triacylglycerols in tobacco, corn, sesame, and soybean seed oils are presented in this application note. By Mehdi Ashraf-Khorassani, Larry T. Taylor, Jinchuan Yang, and Giorgis Isaac

  • Enantiomeric And Diasteriomeric Resolutions Of Chiral Pesticides By ACQUITY UPC2 With UV Detection

    In this application note we have shown the analysis of chiral pesticides using ACQUITY UPC2. ACQUITY UPC2 allows high efficiency separations that can significantly increase the sample throughput when compared with traditional normal-phase separations. By Marian Twohig, Andrew Aubin, Michael O’Leary, Tom DePhillipo, Sherry C. Perine, and David R. Stubbs

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  • Lpath Reports Interim Data From Phase 2a Study For Anti-Cancer Drug, ASONEP

    Lpath, Inc. (NASDAQ: LPTN), the industry leader in bioactive lipid-targeted therapeutics, reported interim results in a Phase 2a single-arm, open-label trial where ASONEP™ is being investigated as a treatment for metastatic renal cell carcinoma (RCC) in patients that have failed at least one therapy involving a VEGF inhibitor (e.g., Sutent®/ sunitinib maleate) and no more than one mTOR inhibitor (e.g., Afinitor®/everolimus), with a maximum of three failed treatments in all



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