DRUG DISCOVERY FEATURED ARTICLES & APPLICATIONS

  • Patheon Surfs Outsourcing Waves And Scoops Up Gallus Along The Way
    Patheon Surfs Outsourcing Waves And Scoops Up Gallus Along The Way

    Jim Mullen, CEO of Patheon parent company DPx Holdings B.V., is at it again.

    On the heels of my three-part series with Mullen on the details behind the springtime merger of his company and the pharmaceutical products division of Royal DSM, he has made his next move.

    This time it is a strategic entrée into the U.S.-based market for biologics services via an acquisition of privately held Gallus BioPharmaceuticals. With Gallus, Patheon adds new capabilities at well-established sites with name-brand clientele, in St. Louis, Mo. and Princeton, N.J., to its global locations in Groningen, the Netherlands and Brisbane, Australia.

  • Systematic Method Development Of UPC2 Conditions Using Opioid Drugs

    This application note uses a panel of natural and synthetic opioid drugs to demonstrate the use of a systematic screening strategy for UPC2 method development. By Jonathan P. Danaceau, Kenneth J. Fountain, and Erin E. Chambers, Waters Corporation

  • A Single-Injection UPC2 Method For Fast And Simultaneous Separation Of Nine Fat-Soluble Vitamins

    Fat-soluble vitamins(FSVs) include vitamins A, D, E, K and carotenoids such as β-carotene. The FSVs are involved in complex metabolic reactions related to important biological functions such as vision (vitamin A), calcium absorption (vitamin D), antioxidant protection of cell membrane (vitamin E), and blood coagulation (vitamin K). By Rui Chen, Jinchuan Yang, and John McCauley, Waters Corporation

  • Lipid Class Separation Using UPC2/MS

    A flexible, universal method was developed for the analysis of inter-class separations of neutral and amphipathetic lipids. By Michael D. Jones, Giorgis Isaac, Giuseppe Astarita, Andrew Aubin, John Shockcor, Vladimir Shulaev, Cristina Legido-Quigley, and Norman Smith

  • Fast Separation Of Triacylglycerols In Oils Using UltraPerformance Convergence Chromatography (UPC2)

    Studies using UPC2 coupled with ultraviolet (UV) detection, mass spectrometry (MS), and evaporative light scattering (ELS) detection for the separation of triacylglycerols in tobacco, corn, sesame, and soybean seed oils are presented in this application note. By Mehdi Ashraf-Khorassani, Larry T. Taylor, Jinchuan Yang, and Giorgis Isaac

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  • Lpath Reports Interim Data From Phase 2a Study For Anti-Cancer Drug, ASONEP

    Lpath, Inc. (NASDAQ: LPTN), the industry leader in bioactive lipid-targeted therapeutics, reported interim results in a Phase 2a single-arm, open-label trial where ASONEP™ is being investigated as a treatment for metastatic renal cell carcinoma (RCC) in patients that have failed at least one therapy involving a VEGF inhibitor (e.g., Sutent®/ sunitinib maleate) and no more than one mTOR inhibitor (e.g., Afinitor®/everolimus), with a maximum of three failed treatments in all

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Controlled-Release Tablets

Controlled-Release Tablets

Whatever challenges these complex technologies present for your project, chances are we have already overcome them in a previous project. Patheon offers the full arc of services and resources to take you seamlessly from early development to market quickly and efficiently.

Personal Pipettor

Personal Pipettor

The PP-150 384-Channel Personal Pipettor automates transfer from the source plate to
Micro Hi-Temp Submersible Logger

Micro Hi-Temp Submersible Logger

The Micro Hi-Temp Submersible Logger can record over 8,000 time-stamped temperature measurements in environments of –40°C to +125°C.
Custom Critical SecureComm™: Cargo Security

Custom Critical SecureComm™: Cargo Security

For the utmost in secure shipping, our 24-hour command center, FedEx Custom Critical SecureComm, can provide additional layers of security and oversight for your medical cargo.

Phospholipid Flashplate Plus

Enables High-Throughput Lipid-Associated Enzyme Assays
AvantGo Mobile Sales

AvantGo Mobile Sales

AvantGo Mobile Sales™ is a customizable, packaged mobile software application that increases sales force productivity and improves the quality of customer interactions.
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