Drug Discovery App CS WP
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Expansion Of Specific Lymphocytes With A Xeno-Free, Serum-Free Medium
4/29/2024
Explore the advantages of utilizing a xeno- and serum-free medium for the targeted expansion of cell subpopulations without the addition of serum.
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Bulk Filling Of Drug Substance | Accurate Aliquoting
4/24/2024
Bulk filling drug substances in traditional facilities is often a lengthy, manual process where operators are relied upon to adjust pump controls to achieve accurate filling. This method, spanning multiple shifts, increases process risk through errors that can compromise accuracy.
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Evaluating CAR T-Cell Therapy Vascular Recruitment, Trafficking, And Killing
4/24/2024
Learn about a more human-relevant platform that enables researchers to assess the trafficking and killing efficiency of immunotherapy as well as the proof-of-concept of immuno-oncology co-therapy.
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Optimizing Human iPSC Aggregate And Organoid Production For Bioprinting
4/17/2024
This study aimed to identify the optimal cell culture conditions to yield high cell density and maintain high cell viability with consistent aggregate morphology and pluripotency marker expression.
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Studying Gut Inflammation And Barrier Disruption With Organ-On-A-Chip Technology
4/9/2024
See how the Colon Intestine-Chip has been employed to model cytokine-mediated inflammation and barrier disruption in the intestine.
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Predicting Human Liver Damage With A More Accurate In Vitro Hepatotoxicity Assay
4/9/2024
This study explores whether a species-specific, multicellular, in vitro hepatotoxicity assays utilizing Liver-Chips can provide a greater understanding of hepatotoxicity mechanisms than animal models.
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Investigating Key Mechanisms Of Parkinson’s With A Novel Model
4/9/2024
Efforts to develop a dynamic “brain-on-a-chip” model that closely resembles the human substantia nigra could be applied to study mechanisms of Parkinson’s disease.
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A Better Immune Response To Vaccination: Using Lymphoid Follicle Organ-Chips
4/9/2024
Discover a first-of-its-kind human LF-Chip containing B, T, plasma and antigen-presenting cells to test functional immunization responses to vaccines and adjuvants in vitro.
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Creating An Effective Pre-Clinical Model Of Bone Marrow
4/9/2024
A Bone Marrow-Chip (BM-Chip) was created to recapitulate relevant hematopoietic cell types in a three-dimensional (3D), mechanically active next-generation in vitro model.
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Revolutionizing Viral Infectious Disease Research And Drug Discovery
4/8/2024
Learn how Organ-Chips are being used to rapidly identify promising treatments, investigate virus evolution, and analyze how mechanical forces influence the innate immune response to viral infections.